[Hypothalamic mechanisms of regulating blood circulation in the coronary and brachial artery systems].

In anesthetized curarized cats effects of high frequency stimulation of anterior, ventromedial, and posterior hypothalamus on arterial blood pressure (ABP) and on perfusion pressure of the coronary and brachial arteries were studied. The stimulation induced vasoconstriction of coronary vessels and increased the ABP. In most experiments, especially in case of stimulation of anterior hypothalamus, simultaneously with increase of perfusion pressure of the coronary artery, a decrease of the brachial artery perfusion pressure was revealed. The mechanism of vasodilatation of the brachial artery seems to be related to a direct inhibition of the tonic activity of the vertebral branch of the ganglion stellatum. The descending influence of the hypothalamus in respect to the activity of the inferior cardiac nerve is mainly facilitatory. Mechanisms of neural control of the regional blood flow in coronary and brachial arteries are discussed.