Internal medicine (Tokyo, Japan) · 2022
Adolescent-onset TAFRO Syndrome with Malignant Nephrosclerosis-like Lesions.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Nakayama Yuki, Mizuno Hiroki, Sawa Naoki, Suwabe Tatsuya, Yamanouchi Masayuki, Ikuma Daisuke, Hasegawa Eiko, Hoshino Junichi, Sekine Akinari, Oba Yuki, Kono Kei, Kinowaki Keiichi, Ohashi Kenichi, Suzuki Kodai, Sato Yasuharu, Shimizu Akira, Yamaguchi Yutaka, Ubara Yoshifumi
Аннотация
A 16-year-old Japanese girl developed a fever, thrombocytopenia, and renal dysfunction. Treatment was started with steroids, but cervical lymphadenopathy and ascites developed. A lymph node biopsy indicated TAFRO syndrome. The patient's renal function deteriorated, and dialysis was started. Refractory hypertension and subsequent encephalopathy developed. Treatment was started with an anti-IL-6 receptor antibody and an anti-CD20 monoclonal antibody. A kidney biopsy showed malignant nephrosclerosis-like microangiopathy and glomerular collapse due to narrowing of the small arteries. The majority of TAFRO syndrome cases are adult-onset, with glomerular microangiopathy. To our knowledge, this is the first report of adolescent-onset TAFRO syndrome presenting with malignant nephrosclerosis-like lesions associated with hypertension.