The Introduction of the vNOTES Hysterectomy in The Netherlands: A Nationwide Cohort Study.

OBJECTIVE

This study aims to assess the peri- and postoperative outcomes of the vNOTES hysterectomy in the Netherlands during implementation.

STUDY

DESIGN

Nationwide cohort study.

SETTING

vNOTES hysterectomies performed in the Netherlands by 15 hospitals since the implementation of the technique, from August 2019 to September 2024.

POPULATION: 673 patients undergoing vNOTES hysterectomy.

METHODS

Descriptive data are presented as frequencies with percentage or mean with range. Logistic regression was used to assess the risk of conversions/complications per BMI group.

MAIN OUTCOME MEASURES: Peri- and postoperative outcomes such as operating time, conversions, and complications.

RESULTS

The mean operating time was 67.4 min (range 24-210). There were 37 (5.5%) conversions and 94 (15.5%) complications. Nineteen (2.8%) complications were perioperative, and 75 (12.7%) postoperative. Ten (1.5%) of the perioperative complications were classified as Clavien-Dindo (CD) 1, and nine (1.3%) as CD3. Postoperatively, 18 patients (3.1%) had a reintervention (N = 17 CD3, N = 1 CD4), and two (0.3%) patients were admitted to the intensive care unit (CD4). The mean blood loss was 127 mL (range 50-2000), and 220 (37%) of patients were discharged the same day.

CONCLUSIONS

This large nationwide cohort study during implementation of the vNOTES hysterectomy demonstrates the safety and feasibility of this upcoming technique, reporting on a short surgery duration and a similar complication percentage compared to other methods of hysterectomy.