Clinical & experimental ophthalmology · 2019
Use of trypan blue as an aqueous tracer dye to investigate hypotony where cyclodialysis cleft is suspected.
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Khoo Ying J, Abdullah Aulia A H, Yu Dao-Yi, Morgan William H
Аннотация
IMPORTANCE: A new method to help diagnose suspected cyclodialysis clefts.
BACKGROUND: To study the use of trypan blue stained aqueous flow patterns in diagnosing causes of hypotony where cyclodialysis clefts were suspected.
DESIGN: A case series in a tertiary care centre.
PARTICIPANTS: Ten subjects presenting with persistent hypotony and retinal changes.
METHODS: Trypan blue was injected into the anterior chamber.
MAIN OUTCOME MEASURES: The pattern of dye flow in the anterior chamber was categorized. Intraocular pressure prior to surgery was recorded.
RESULTS: All seven subjects with cyclodialysis clefts had a preferential flow to the cleft region. Two hypotonous subjects post trabeculectomy had rapid (5 seconds) and extensive lymphatic staining (6 o'clock hours extent) without visible bleb formation.
CONCLUSIONS AND RELEVANCE: Preferential flow of dye to the limbus is a reliable sign of cyclodialysis cleft and helps localize cleft extent. A new cause of hypotony, "lymphatic overdrain," is identified.
BACKGROUND: To study the use of trypan blue stained aqueous flow patterns in diagnosing causes of hypotony where cyclodialysis clefts were suspected.
DESIGN: A case series in a tertiary care centre.
PARTICIPANTS: Ten subjects presenting with persistent hypotony and retinal changes.
METHODS: Trypan blue was injected into the anterior chamber.
MAIN OUTCOME MEASURES: The pattern of dye flow in the anterior chamber was categorized. Intraocular pressure prior to surgery was recorded.
RESULTS: All seven subjects with cyclodialysis clefts had a preferential flow to the cleft region. Two hypotonous subjects post trabeculectomy had rapid (5 seconds) and extensive lymphatic staining (6 o'clock hours extent) without visible bleb formation.
CONCLUSIONS AND RELEVANCE: Preferential flow of dye to the limbus is a reliable sign of cyclodialysis cleft and helps localize cleft extent. A new cause of hypotony, "lymphatic overdrain," is identified.