BMJ neurology open · 2021
Clinical and magnetic resonance study of a case of subacute sclerosing panencephalitis treated with ketogenic diet.
СтатьяНазвание и аннотация: Перевод в очереди
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Valente Mariarosaria, Del Negro Ilaria, Bagatto Daniele, Garbo Riccardo, Lettieri Christian, Bernardini Andrea, Nilo Annacarmen, Peri Maria Rosaria, Pecori Davide, Gigli Gian Luigi
Аннотация
BACKGROUND: Subacute sclerosing panencephalitis is a progressive neurodegenerative disorder caused by a latent and mutant measles virus which is extremely rare in developed countries. The lack of effective treatments leads to the research of other anti-inflammatory and neuroprotective treatments.
CASE: Here we present a case of a 17-year-old patient affected by subacute sclerosing panencephalitis who manifest a dramatic improvement in neurological and general clinical conditions, as well as an arrest in the progression of demyelinating process in the central nervous system, after the beginning of a high ratio ketogenic diet.
CONCLUSIONS: Given its anti-inflammatory, antioxidant and metabolic effects, we believe that ketogenic diet utilisation could be a rational approach, can be considered a safe add-on therapy, carrying on with only a minimal risk of adverse effects or interactions.
CASE: Here we present a case of a 17-year-old patient affected by subacute sclerosing panencephalitis who manifest a dramatic improvement in neurological and general clinical conditions, as well as an arrest in the progression of demyelinating process in the central nervous system, after the beginning of a high ratio ketogenic diet.
CONCLUSIONS: Given its anti-inflammatory, antioxidant and metabolic effects, we believe that ketogenic diet utilisation could be a rational approach, can be considered a safe add-on therapy, carrying on with only a minimal risk of adverse effects or interactions.