Медицинская библиотека · Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2002

[Role of thyroid hormone in peripheral nerve regeneration].

Wang Min, Yang Zhi-huan

Аннотация на английскомСтатьяПеревод в очереди

Аннотация

OBJECTIVE

To review the role of thyroid hormone in the peripheral nerve regeneration.

METHODS

The recent literatures of experimental study and clinical application on the role of thyroid hormone in nerve regeneration were reviewed. The researches on expression, isoform and changes of thyroid hormones in rat sciatic nerve in normal or injury were summarized. The effect of thyroid hormone on local rat sciatic nerve was studied, too.

RESULTS

Nuclear thyroid hormone receptors expressed in numerous nuclei of sciatic nerve during a limited period of development extending from the third week of embryonic life to the end of the second postnatal week and after injury of adult sciatic nerve. A single and local administration of thyroid hormone at the level of the transected sciatic nerve produced a lasting effect on peripheral nerve regeneration.

CONCLUSION

The beneficial effects of thyroid hormones upon injured peripheral nerve may have considerable therapeutic potential.

Для цитирования: Wang Min, Yang Zhi-huan. [Role of thyroid hormone in peripheral nerve regeneration].. Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery. 2002.

Предметные рубрики MeSH

Animals Nerve Regeneration Peripheral Nerves Rats Receptors, Thyroid Hormone Schwann Cells Sciatic Nerve Thyroid Hormones Triiodothyronine

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