Медицинская библиотека · Zhonghua nan ke xue = National journal of andrology · 2011

[Sperm DNA damage and unexplained recurrent spontaneous abortion].

Liu Cheng-Jun, Wang Ai-Ming, Shang Wei, Li Min, Wang Wei-Zhou, Shen Yu-Liang, Zhao Yong

Аннотация на английскомСтатьяПеревод в очереди

Аннотация

OBJECTIVE

To explore the relationship of sperm DNA damage with unexplained recurrent spontaneous abortion (URSA).

METHODS

Sperm DNA fragmentation was evaluated by sperm chromatin dispersion (SCD), and the results were expressed in terms of DNA fragmentation index (DFI). DFIs were measured in the male partners of 56 women with URSA (the experiment group) and of 31 without URSA (the control group).

RESULTS

The DFI was shown to be (11.0% - 56.9%) in the experiment group, 21 (37.5%) of the subjects over 30%, as compared with (10.0% -36.8%) in the control group, only 8 (25.8%) of the subjects over 30%, significantly higher in the former than in the latter (29.4% vs 25.5%, P < 0.05).

CONCLUSION

There is a relationship between sperm DNA damage and URSA.

Для цитирования: Liu Cheng-Jun, Wang Ai-Ming, Shang Wei, Li Min, Wang Wei-Zhou, Shen Yu-Liang, Zhao Yong. [Sperm DNA damage and unexplained recurrent spontaneous abortion].. Zhonghua nan ke xue = National journal of andrology. 2011.

Предметные рубрики MeSH

Abortion, Habitual Adult Case-Control Studies DNA Damage DNA Fragmentation Female Humans Male Pregnancy Spermatozoa

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