Anesteziologiia i reanimatologiia · 2011
[Cardioprotective properties of sevoflurane in coronary bypass surgery with extracorporeal circulation].
Сравнительное исследованиеКонтролируемое клиническое исследованиеСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Аннотация
UNLABELLED: The aim of the study is to investigate cardioprotective properties of sevoflurne during coronary bypass surgery with extracorporeal circulation.
METHODS: 60 patients with coronary heart disease (left ventricular ejection fraction 61,3+1,0%) underwent surgery with extracorporeal circulation. Inhalation anesthesia with Sevoflurane and TIVA were performed. Hemodynamic, troponin level, KFK, protein of heart shock in plasma (PHS 70) and PHS in myocard were monitored.
RESULTS: patients who were administrated with Sevoflurane had lower level of troponin than patients of second group. In postperfusion period the amount of PHS 70 in myocard increased in 1.6 times than in preperfusion period in comparison to TIVA method this figure did not change. There was negative correlation in level of PHS 70 in plasma and troponin in first day after the operation (r = -0,61 p < 0,05) and second day (r = - 0,76, p < 0,05). In conclusion Sevoflurane had affected hemodynamic less than TIVA. Increased level of PHS has cardioprotective effects.
METHODS: 60 patients with coronary heart disease (left ventricular ejection fraction 61,3+1,0%) underwent surgery with extracorporeal circulation. Inhalation anesthesia with Sevoflurane and TIVA were performed. Hemodynamic, troponin level, KFK, protein of heart shock in plasma (PHS 70) and PHS in myocard were monitored.
RESULTS: patients who were administrated with Sevoflurane had lower level of troponin than patients of second group. In postperfusion period the amount of PHS 70 in myocard increased in 1.6 times than in preperfusion period in comparison to TIVA method this figure did not change. There was negative correlation in level of PHS 70 in plasma and troponin in first day after the operation (r = -0,61 p < 0,05) and second day (r = - 0,76, p < 0,05). In conclusion Sevoflurane had affected hemodynamic less than TIVA. Increased level of PHS has cardioprotective effects.