Arterial-Ventricular Coupling Evaluation in Individuals with Stress-Evidenced Diastolic Dysfunction: A Pilot Study.

INTRODUCTION

Arterial-ventricular coupling (AVC) has been recognized as a key determinant of global cardiovascular performance. Diastolic dysfunction (DD) occurs when inadequate filling of the ventricles is related to an abnormal elevation of intracardiac filling pressures. In some cases, DD is evidenced during cardiac stress, provoked by exercise.

OBJECTIVE

To evaluate AVC in individuals with stress evidenced DD, in relation to controls.

MATERIALS AND

METHODS

Stress echocardiography was applied to assess cardiac function during exercise. Arterial-ventricular coupling was evaluated, based on the assessment of left ventricular and arterial elastances.

RESULTS

AVC showed a significant difference at peak exercise compared to controls, basically due to a loss of cardiac contractility.

CONCLUSION

The manifestation of AVC coupling imbalance could act as a complementary parameter to support the diagnosis of DD.