Medecine et maladies infectieuses · 2017
Antibiotic susceptibility of probiotic strains: Is it reasonable to combine probiotics with antibiotics?
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Neut C, Mahieux S, Dubreuil L J
Аннотация
OBJECTIVE: The main goal of this study was to determine the in vitro susceptibility of strains collected from marketed probiotics to antibiotics used to treat community-acquired infections.
METHODS: The minimum inhibitory concentrations (MICs) of 16 antibiotics were determined using a gradient strip (E test) or the agar dilution method for fidaxomicin.
RESULTS: The probiotics demonstrated various antibiotic patterns. Bacterial probiotics are generally susceptible to most prescribed antibiotics orally administered, whereas yeast probiotics, such as Saccharomyces boulardii, are resistant.
CONCLUSION: Special attention must be paid to co-prescriptions of antibiotics and probiotics to ensure that the probiotic strain is not susceptible.
METHODS: The minimum inhibitory concentrations (MICs) of 16 antibiotics were determined using a gradient strip (E test) or the agar dilution method for fidaxomicin.
RESULTS: The probiotics demonstrated various antibiotic patterns. Bacterial probiotics are generally susceptible to most prescribed antibiotics orally administered, whereas yeast probiotics, such as Saccharomyces boulardii, are resistant.
CONCLUSION: Special attention must be paid to co-prescriptions of antibiotics and probiotics to ensure that the probiotic strain is not susceptible.