Regional anesthesia · 1994
Subarachnoid labor analgesia. Fentanyl and morphine versus sufentanil and morphine.
Клиническое исследованиеСравнительное исследованиеСтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Arkoosh V A, Sharkey S J, Norris M C, Isaacson W, Honet J E, Leighton B L
Аннотация
BACKGROUND AND OBJECTIVES: To compare the duration of pain relief and incidence of side effects using two subarachnoid administered drug combinations for labor analgesia: fentanyl 25 micrograms with morphine 0.25 mg or sufentanil 10 micrograms with morphine 0.25 mg.
METHODS: Thirty healthy term primagravid patients with cervical dilation < or = 5 cm consented to participate in this prospective, randomized, double-blind study. Patients received the assigned drug combination subarachnoid with simultaneous epidural catheter placement using a double needle technique. The authors recorded blood pressure and patient's rated pain, nausea, and pruritus using 10-cm visual analog scales at 0, 5, 10, 15, 20, 25, 30, and every 30 minutes until the patient requested additional analgesia.
RESULTS: The onset of analgesia was rapid in both groups. The mean duration of analgesia was similar; 114 +/- 55 minutes in the fentanyl and morphine group and 134 +/- 79 minutes in the sufentanil and morphine group. The sufentanil and morphine group experienced more severe pruritus (P = .015).
CONCLUSIONS: Both fentanyl and morphine and sufentanil and morphine provide adequate labor analgesia for about 2 hours. Patients who receive sufentanil experience more severe pruritus.
METHODS: Thirty healthy term primagravid patients with cervical dilation < or = 5 cm consented to participate in this prospective, randomized, double-blind study. Patients received the assigned drug combination subarachnoid with simultaneous epidural catheter placement using a double needle technique. The authors recorded blood pressure and patient's rated pain, nausea, and pruritus using 10-cm visual analog scales at 0, 5, 10, 15, 20, 25, 30, and every 30 minutes until the patient requested additional analgesia.
RESULTS: The onset of analgesia was rapid in both groups. The mean duration of analgesia was similar; 114 +/- 55 minutes in the fentanyl and morphine group and 134 +/- 79 minutes in the sufentanil and morphine group. The sufentanil and morphine group experienced more severe pruritus (P = .015).
CONCLUSIONS: Both fentanyl and morphine and sufentanil and morphine provide adequate labor analgesia for about 2 hours. Patients who receive sufentanil experience more severe pruritus.