Metal-Organic Skeleton-Derived W-Doped Ga2O3-NC Catalysts for Aerobic Oxidative Dehydrogenation of N-Heterocycles.

N-heterocycles with quinoline structures hold significant importance within the chemical and pharmaceutical industries. However, achieving their efficient transformations remains a vital yet challenging endeavor. Herein, a series of W-doped Ga2O3-NC catalysts were synthesized using a Ga-MOF-derived strategy through a simple solvothermal method, with a remarkably high activity and selectivity towards the oxidative dehydrogenation of N-heterocycles. Furthermore, the MOF-derived W-doped Ga2O3-NC catalysts exhibit remarkable substrate tolerance and recyclability. The outstanding catalytic activity was attributed to the robust synergistic interaction between the W species and the Ga2O3-NC carrier, which facilitates the activation of hydrogen atoms in the C-H and C=N bonds on both the oxygen molecule and the substrate to produce H2O2. Additionally, the solvent effect of methanol can significantly enhance dehydrogenation due to its strong ability to donate and accept protons of hydrogen bonding. The present work provides a new approach to MOF-derived non-precious metal catalysts for achieving the efficient oxidation dehydrogenation of N-heterocycles.