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DOI 10.1007/s00520-022-07290-1

Медицинская библиотека · Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022

Effect of accelerated rehabilitation combined with enteral nutrition on gastrointestinal function recovery after hepatectomy.

Qiu Jingjing, Wang Youhong

Рандомизированное исследованиеСтатьяПеревод в очереди

Аннотация

OBJECTIVE

To investigate the effect of accelerated rehabilitation combined with enteral nutrition on the recovery of gastrointestinal function in patients after hepatectomy.

METHODS

In this prospective randomized controlled study, a total of 108 patients with liver cancer who underwent hepatectomy in our hospital from November 2020 to December 2021 were selected as the research subjects. According to the random number table method, the patients were divided into a research group (54 cases, who received accelerated rehabilitation combined with enteral nutrition) and a control group (54 cases, who received routine nursing without enteral nutrition). The gastrointestinal function of patients in two groups was recorded and compared, the nutritional status before and after surgery was compared, and the levels of T cell subsets CD3+, CD4+, CD8+, CD4+/CD8+, and liver function were compared between the two groups. The adverse reactions such as catheter infection, diarrhea, vomiting, intestinal obstruction, and ascites occurred in two groups were recorded.

RESULTS

The gastrointestinal function of patients in research group was significantly better than that in control group (P < 0.05). After intervention, the albumin (ALB) in research group was significantly higher than that in control group (P < 0.05), but no significant difference in body weight between two groups was found (P > 0.05). After intervention, CD3+, CD4+, CD8+, and CD4+/CD8+ in the research group were significantly higher than those in the control group (P < 0.05). In addition, there was no significant difference in liver function indexes between the two groups (P > 0.05); however, the incidence of adverse reactions in research group was significantly lower than that in the control group (P < 0.05).

CONCLUSION

Accelerated rehabilitation combined with enteral nutrition can effectively restore the gastrointestinal function of patients after hepatectomy, which is worthy of clinical promotion.

Для цитирования: Qiu Jingjing, Wang Youhong. Effect of accelerated rehabilitation combined with enteral nutrition on gastrointestinal function recovery after hepatectomy.. Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer. 2022. DOI: 10.1007/s00520-022-07290-1.

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