The role of CPK isoenzymes in predicting extrauterine early pregnancy.

OBJECTIVE

To evaluate the ability of Creatine phosphokinase (CPK) levels and CPK-MB proportion to differentiate between extra and intrauterine of very early gestations with unknown location.

MATERIALS AND

METHODS

The study is case-control. CPK levels and CPK-MB proportion in 51 women with extrauterine pregnancies were compared to those in 28 women with early intrauterine pregnancies.

RESULTS

No significant difference was found between women with extrauterine pregnancies and early intrauterine pregnancies in the levels of CPK (80.9 ± 62.1 vs. 74.9 ± 51.5; p = 0.66) and CPK-MB proportion (16.2 ± 10.1% vs. 15.1 ± 11.1%; p = 0.86).

CONCLUSION

CPK and CPK-MB proportion determinations do not contribute to the clinical differentiation between early intra and extrauterine pregnancies.