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Войти в исследования Serological profile of John Cunningham virus (JCV) in patients with multiple sclerosis.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Branco Luciana Prats, Adoni Tarso, Apostolos-Pereira Samira Luisa, Brooks Joseph Bruno Bidin, Correa Eber Castro, Damasceno Carlos Augusto, Eboni Audred Cristina Biondo, Fezer Leticia, Gama Paulo Diniz da, Goncalves Marcus Vinicius Magno, Gomes Sidney, Grzesiuk Anderson Kuntz, Mendes Maria Fernanda, Morales Rogerio Rizo, Muniz Andre, Parolin Monica Fiuza Koncke, Pimentel Maria Lucia Vellutini, Ribeiro Marlise de Castro, Santos Gutemberg Augusto Cruz Dos, Sato Henry Koiti, Scherpenhuijzen Simone Batista, Scorcine Claudio, Siquineli Fabio, Sousa Nise Alexandra de Carvalho, Varela Daniel Lima, Winckler Tereza Cristina Avila, Fragoso Yara Dadalti
Аннотация
OBJECTIVE: To identify the serologic profile of JCV in patients with MS.
METHODS: Data on serum antibodies for JCV were obtained using the enzyme-linked immunosorbent assay provided by the STRATIFY-JCV program.
RESULTS: A total of 1,501 blood tests were obtained from 1,102 patients with MS. There were 633 patients (57.1%) who were positive for antibodies for JCV and 469 patients who were negative (42.9%). Twenty-three patients became positive after initially having negative JCV antibody status. The rate of seroconversion was 18.5% over 22 months.
CONCLUSION: The JCV serologic profile and seroconversion in Brazilian patients were similar to those described in other countries.