The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2010
Can we use neopterin as marker of viral infections in pregnant women with symptoms of imminent spontaneous abortion?
Оценочное исследованиеСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
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Bogavac Mirjana A, Brkic Snezana, Simin Natasa, Nikolic Aleksandra, Grujic Zorica, Milosevic Vesna, Bozin Biljana
Аннотация
PURPOSE: To find out if determination of neopterin can be used for the detection of viral infections in pregnant women with symptoms of imminent spontaneous abortion.
METHODS: Eighty-eight pregnant women with symptoms of imminent spontaneous abortion (investigated group) and 88 healthy pregnant women were evaluated (control group). Neopterin level and IgM and IgG antibodies for eight viruses in the blood were determined.
RESULTS: Parvo B19 virus and elevated neopterin values were found in significantly higher number in investigated group than in control. There was no correlation between women with acute ParvoB19 infection and elevated neopterin level.
CONCLUSIONS: The determination of neopterin in the sera cannot be used for screening of viral infections in pregnancy.
METHODS: Eighty-eight pregnant women with symptoms of imminent spontaneous abortion (investigated group) and 88 healthy pregnant women were evaluated (control group). Neopterin level and IgM and IgG antibodies for eight viruses in the blood were determined.
RESULTS: Parvo B19 virus and elevated neopterin values were found in significantly higher number in investigated group than in control. There was no correlation between women with acute ParvoB19 infection and elevated neopterin level.
CONCLUSIONS: The determination of neopterin in the sera cannot be used for screening of viral infections in pregnancy.