Expert opinion on pharmacotherapy · 2009
Treatment strategies for oropharyngeal candidiasis.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
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Laudenbach Joel M, Epstein Joel B
Аннотация
BACKGROUND: Oropharyngeal candidiasis (OPC) is a common oral disease that may cause oral symptoms, lead to regional infection (e.g., esophageal candidiasis) and increase the risk of systemic fungal infection in the compromised host.
OBJECTIVE: Critical review of the literature of prevention and therapy.
METHODS: The literature was reviewed using PubMed, and specific keywords from the MeSH Database were used.
RESULTS/CONCLUSION: Management of OPC requires that the underlying risk factors of infection be diagnosed and managed whenever possible. Antimicrobials may be provided as topical or systemic therapy. Topical therapies may provide effective management for candidiasis in the non-compromised host and increase the control of colonization in the compromised host. Advances in prevention and management include new agents and improved mechanisms of topical drug delivery.
OBJECTIVE: Critical review of the literature of prevention and therapy.
METHODS: The literature was reviewed using PubMed, and specific keywords from the MeSH Database were used.
RESULTS/CONCLUSION: Management of OPC requires that the underlying risk factors of infection be diagnosed and managed whenever possible. Antimicrobials may be provided as topical or systemic therapy. Topical therapies may provide effective management for candidiasis in the non-compromised host and increase the control of colonization in the compromised host. Advances in prevention and management include new agents and improved mechanisms of topical drug delivery.