Diabetic foot ulcerations: management and adjunctive therapy.

Foot ulcerations, infections, gangrene, and lower extremity amputation are major causes of disability to the patient who has diabetes mellitus, often resulting in significant morbidity, extensive periods of hospitalization, and mortality. Although not all such lesions can be prevented, it is possible to dramatically reduce their incidence through appropriate management and prevention protocols incorporating a multidisciplinary team approach.