[The relationship between sleep related breathing disorders and stroke].

OBJECTIVE

To study the relationship between sleep related breathing disorder(SRBD) and cerebrovascular diseases (CVD).

METHODS

Polysomnographic studies on 43 cases of CVD were performed and 43 sex-, age-, body mass index- compatible cases without CVD used as controls.

RESULTS

The incidence of SRBD (mostly the obstructive one) was much more in CVD patients and both the obstructive and central apnea/hypopnea indices, deoxygenation indices were bigger and deoxygenation time were longer while the mean and lowest oxygen saturation were lower in CVD group than those in the controls (all P < 0.05). The blood pressure before sleep, after awakening and the mean BP during sleep were also higher in the CVD patients. In CVD group, the incidence of hypertension was also much higher in SRBD patients than that in non-SRBD ones (P < 0.01). SRBD was dangerous for CVD as OR value was 6.28.

CONCLUSIONS

SRBD may be one important risk factor for CVD. An vicious circle might be formed between stroke and SRBD which inflences the outcome of stroke.