[Radiological study of metaphyso-epiphyseal anomalies in osteogenesis imperfecta. Apropos of 61 cases].

The object of the present study was to examine all the metaphyseal and epiphysial abnormalities from sixty one patients with osteogenesis imperfecta. Regarding the growing ends of the bones, eight of the 61 children (13%) had disorders in the epiphyseal ends of the bones. The development of the radiological features can be divided into three stages. The last one is characterized by a severe epiphyseal deformation. Histologically there is a disorderly proliferation of the calcified cartilage at the center of the epiphyses. Several physio-pathological hypothesis may be advanced, and particularly the responsibility of the vascular upsets secondary to fractures.