Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2009
The use of voriconazole in the management of post-penetrating keratoplasty Paecilomyces keratitis.
Клинический случайСтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Deng Sophie X, Kamal Khairidzan M, Hollander David A
Аннотация
PURPOSE: The aim of this study was to report successful treatment of Paecilomyces lilacinus keratitis with voriconazole.
METHOD: Case series.
RESULTS: Two patients with history of penetrating keratoplasty (PKP) presented with progressive P. lilacinus keratitis. Initial medical treatment failed to control the infection. The first patient received topical voriconazole at the early stage of infection. The second patient required therapeutic PKP and intracameral voriconazole was given at the end of the surgery. He developed presumed secondary endophthalmitis and was treated aggressively with intravitreal and systemic voriconazole. Both the patients responded well to the treatment and achieved complete recovery.
CONCLUSIONS: These cases illustrated effectiveness and safety of various modes of voriconazole administration in treating P. lilacinus ocular infection.
METHOD: Case series.
RESULTS: Two patients with history of penetrating keratoplasty (PKP) presented with progressive P. lilacinus keratitis. Initial medical treatment failed to control the infection. The first patient received topical voriconazole at the early stage of infection. The second patient required therapeutic PKP and intracameral voriconazole was given at the end of the surgery. He developed presumed secondary endophthalmitis and was treated aggressively with intravitreal and systemic voriconazole. Both the patients responded well to the treatment and achieved complete recovery.
CONCLUSIONS: These cases illustrated effectiveness and safety of various modes of voriconazole administration in treating P. lilacinus ocular infection.