Медицинская библиотека · Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2009

[Changes of peripheral blood chromosomal centromere aberration in patients with cytomegalovirus infection after anti-viral treatment].

Gao Lan, Liu Yan-hui, Li Li-fen, Wu Ya-min, Wang Ming-bo, Shi Jing, Yuan Bing, Song Juan, He Yong-ming, Wei Dai-kui

Аннотация на английскомСтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

OBJECTIVE

To study the changes of peripheral blood chromosomal centromere aberration in patents with cytomegalovirus (CMV) infection after anti-viral treatment.

METHODS

Sixty-two patients with early spontaneous abortion and CMV infection analyzed for their peripheral blood chromosomal centromere using simultaneous silver staining before and after anti-viral treatment.

RESULTS

The patients with CMV infection had high rate of centromere aberration, which was decreased significantly after anti-viral treatment (P<0.0001).

CONCLUSION

CMV infection is a risk factor for peripheral blood chromosomal centrimere aberration. Anti-viral treatment can decrease the rate of centrimere aberration aberration. Detection of peripheral blood chromosomal centrimere aberration allows the assessment of the severity of infection and the condition after treatment.

Для цитирования: Gao Lan, Liu Yan-hui, Li Li-fen, Wu Ya-min, Wang Ming-bo, Shi Jing, Yuan Bing, Song Juan, He Yong-ming, Wei Dai-kui. [Changes of peripheral blood chromosomal centromere aberration in patients with cytomegalovirus infection after anti-viral treatment].. Nan fang yi ke da xue xue bao = Journal of Southern Medical University. 2009.

Предметные рубрики MeSH

Abortion, Spontaneous Adult Antiviral Agents Centromere Chromosome Aberrations Cytomegalovirus Infections Female Humans Pregnancy Pregnancy Complications, Infectious Young Adult

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