Horses, hounds and hydrophobia: Henry Bracken's 'strict enquiry' to compare two treatments for rabies in dogs (1737).

IntroductionHenry Bracken M.D. (1697-1764) was born in the Horse and Farrier inn, Lancaster, England. He completed his apprenticeship in Wigan and studied at St Thomas' Hospital (London), the Hôtel Dieu (Paris) and Leiden (Holland). Bracken published books on farriery, urological stones and midwifery.AimsTo examine Bracken's 1737 controlled trial of two treatments for rabies in houndsMethodHistorical literature reviewResultsBracken's 'strict enquiry' compared treatments in two groups of 'an equal number' of hounds 'equally affected as far as could be judged' [i.e. at risk of developing rabies]. One received a herbal 'decoction' and the other a 'secret' powder sold by Mr Hill of Ormskirk. Bracken offers quantitative outcomes: 'Five out of Nine of Mr. Hill's died, and those under the [herbal treatment] all recover'd'.ConclusionWe speculate that Mr Hill's powder contained mercury, causing salivation which was mistaken for clinical signs of rabies. Finally, we also examine Bracken's notion of vocation that 'a Man is born a Physician as well as a Poet'. We conclude that it is harder in modern societies for young people to recognise an early inkling towards a career in medicine. Unlike Bracken's 'inborn' calling, vocation today is more likely to be perceived in terms of a 'transaction', e.g. a 'career move' or 'lifestyle choice'.