Kikuchi-Fujimoto's disease: a report of five cases.

Kikuchi Fujimoto's disease is a rare, self limiting disorder characterized by fever and cervical lymphadenitis. It is often an incidental finding in a patient suspected to have tuberculosis or lymphoproliferative disorder. We diagnosed this disease in a young 23-year-old female who was suffering from prolonged fever, cervical lymphadenopathy, anemia, leucopenia and mild splenomegaly; based on histopathological study of the excised lymphnode. We reviewed the clinical records and histopathologic findings of four more patients of Kikuchi-Fujimoto's disease, who were treated by others at our institute. All five patients improved with NSAIDS (non steroidal anti inflammatory drugs). Histopathological finding of histiocytic necrotizing lymphadenitis or Kikuchi's disease proved invaluable in characterization of these cases.