Anaesthetic or "Antiaesthetic" or "Antaesthetic"? Correspondence From Andrew Buchanan, MD, to James Simpson, MD, Concerning a Name for the Agents Producing Insensibility.

In November 1847, James Young Simpson, MD, of Edinburgh, Scotland, applied the word anaesthesia to the state of narcotism and insensibility produced by the inhaled vapors of sulfuric ether and chloroform, along with the word anaesthetic as an adjective to denote that state and as a generic term for agents capable of inducing the state of insensibility. In March 1848, Andrew Buchanan, MD, of Glasgow, Scotland, penned a letter to Simpson to suggest a more semantically precise word, the spelling of which is not clear in Buchanan's letter. We do not know whether Simpson replied to Buchanan. Simpson continued using the words anaesthesia and anaesthetic in his publications.