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European heart journal. Case reports · 2022

Fulminant myocarditis after the first dose of mRNA-1273 vaccination in a patient with previous COVID-19: a case report.

Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Horiuchi Kohei, Kosugi Shumpei, Abe Haruhiko, Ueda Yasunori

Аннотация

BACKGROUND: COVID-19 vaccines have shown success in protecting people worldwide, although serious adverse effects have been reported in very rare cases.

CASE SUMMARY: A 32-year-old male with a prior medical history of mild COVID-19 infection developed fulminant myocarditis five days after mRNA-1273 vaccination (first dose), which was confirmed using endomyocardial biopsy. He acutely developed respiratory failure and cardiogenic shock with ventricular tachycardia, but recovered completely with short-term high-dose steroid therapy and mechanical cardiac support, which is the recommended treatment for fulminant lymphocytic myocarditis.

DISCUSSION: COVID-19 vaccine-induced myocarditis varies from mild to severe. In the present case, the patient was treated as for fulminant lymphocytic myocarditis and recovered relatively quickly. The mechanism of COVID-19 vaccine-associated myocarditis needs to be urgently investigated.

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

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