[The clinical picture and therapy of nodular mastocytosis].

The authors review the literature data on and describe 6 cases of nodular mastocytosis presenting as multiple blending nodes. The patients (2 girls and 4 boys aged under 4) have developed a disseminated process with multiple nodes up to 3.0-3.5 cm in diameter colored brownish or yellowish, mostly with a smooth surface, localized on the hairy part of the head, trunk, and limbs. Some nodes blended to form larger foci of lesions, particularly on the back and in large skin folds. In 5 patients the diagnosis has been confirmed histologically. No visceral or systemic abnormalities have been revealed. Enlarged (pea-size) inguinal and cubital lymph nodes have been detected in one child. Zaditen therapy has been fairly effective.