Comparing the Efficiency of Microneedling and Tranexamic Acid Versus Microneedling and Vitamin C in the Treatment of Infraorbital Hyperpigmentation.

BACKGROUND

Infraorbital hyperpigmentation is a common condition, and due to its multifactorial nature, it is less responsive to standard treatments. Therefore, the aim of our research was to evaluate the efficiency of microneedling and tranexamic acid with microneedling and vitamin C in the treatment of dark circles around the eyes.

MATERIALS AND

METHODS

The present research was a prospective, single-blind, randomized clinical trial. Thirty-seven female candidates who had been referred to the skin clinic of Imam Hospital of Ahvaz for treating dark circles around their eyes were included. People were divided into two groups on both sides under the eyes (right and left). For randomization, in treatment method A, microneedling and tranexamic acid were used for the right side of patient's face, microneedling and vitamin C treatment for the left side, and the opposite was considered for group B. All analyses were performed using SPSS version 22 software.

RESULTS

Both methods presented dramatic advancement in all sessions compared to the baseline. There was no remarkable difference between the two groups regarding treatment methods (P = 0.444). The patients' consent showed no considerable difference between the two sides. Unfavorable incidents were non-permanent, with no dramatic diversity between both sides except for burning that lasted longer with microneedling and vitamin C.

CONCLUSION

Both tranexamic acid and vitamin C, in combination with microneedling, appear to be impressive modalities for the management of infraorbital hyperpigmentation with no remarkable side effects.