Extra-mammary Paget's disease of the scrotum and penis: a case report.

Extra-mammary Paget's disease is a rare disease mainly observed in elderly patients. It is an intra-epithelial adenocarcinoma that involves the area rich in apocrine glands. The most common affected lesions are the vulva and perianal region, followed by the axillae and inguinoscrotal area. Mostly, extra-mammary Paget's disease is restricted to the epidermis, but advanced invasion to the dermis is possible with a poor prognosis of disease. The associated occult malignancy is reported and often exists for more than 10 years without clinical manifestation. We report a case of a 66-year-old male with extra-mammary Paget's disease of the scrotum and penis. The diagnosis and treatment are discussed.