[Detoxification in the combined intensive therapy of patients with multiple organ failure].

Studies of the influence of the UV irradiation of autologous blood (UVIAB) and hemosorption (HS) upon changes of indices of endogenous intoxication in patients with the syndrome of polyorganic insufficiency (SPOI) have shown that the isolated (without HS) UVIAB reduces toxemia and prevents the development of SPOI in patients without pronounced alterations of microcirculation. Using the UV irradiation of autoblood in patients with clinically marked alterations of the peripheral blood circulation increases toxemia at the expense of release of toxic products from the "disclosed" system of microcirculation. HS with the simultaneous taking the blood from the subclavian vein and abdominal aorta with using "Actilen" and return of the mixed blood into the peripheral artery interrupts and relieves the course of SPOI.