Annals of vascular surgery · 2025
Application of Restrictive Fluid Resuscitation in Emergency Traumatic Hemorrhagic Shock and Impact on Blood Gas Indicators.
СтатьяСравнительное исследованиеНазвание и аннотация: Перевод в очереди
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Li Lin, Zhou Jiehao, Song Kun, Liu Hongbo, Wang Xiao, Zhu Yuqian, Wang Zhijun
Аннотация
BACKGROUND: The study aimed to observe the application of restrictive fluid resuscitation in emergency traumatic hemorrhagic shock (THS) and impact on blood gas indicators.
METHODS: THS patients (n = 80) were divided into two groups: 40 cases in the active group received active fluid resuscitation, and 40 cases in the restricted group received restrictive fluid resuscitation. Blood gas indicators (blood lactate, partial pressure of arterial blood carbon dioxide, and partial pressure of arterial blood oxygen), coagulation parameters (activated partial thromboplastin time, prothrombin time, and thromboplastin time), inflammation indicators (interleukin [IL]-6, IL-8, and tumor necrosis factor-α) levels, complications, and resuscitation outcomes in the two groups were compared.
RESULTS: After 24 h of resuscitation in both groups, blood lactate and partial pressure of arterial blood carbon dioxide decreased and partial pressure of arterial blood oxygen increased, and all of them were significantly improved in the restricted group compared with the active group. Activated partial thromboplastin time, prothrombin time, and thromboplastin time were prolonged, but were shorter in the restricted group than in the active group. Serum IL-6, IL-8, and tumor necrosis factor-α levels were reduced in both groups and were lower in the restricted group than in the active group. The overall incidence of complications within 1 week of resuscitation was 7.50% (3/40) in the restricted group, which was lower than 25.00% (10/40) in the active group. The success rate of resuscitation within 1 week after resuscitation was 95.00% (38/40) higher in the restricted group than 77.50% (31/40) in the active group (all P < 0.05).
CONCLUSION: Compared with active fluid resuscitation, restrictive fluid resuscitation applied in the emergency treatment of THS patients has a better effect on the improvement of patients' blood gas indices, coagulation indices, and inflammation indices, and can effectively reduce the incidence of complications and enhance the success rate of resuscitation.
METHODS: THS patients (n = 80) were divided into two groups: 40 cases in the active group received active fluid resuscitation, and 40 cases in the restricted group received restrictive fluid resuscitation. Blood gas indicators (blood lactate, partial pressure of arterial blood carbon dioxide, and partial pressure of arterial blood oxygen), coagulation parameters (activated partial thromboplastin time, prothrombin time, and thromboplastin time), inflammation indicators (interleukin [IL]-6, IL-8, and tumor necrosis factor-α) levels, complications, and resuscitation outcomes in the two groups were compared.
RESULTS: After 24 h of resuscitation in both groups, blood lactate and partial pressure of arterial blood carbon dioxide decreased and partial pressure of arterial blood oxygen increased, and all of them were significantly improved in the restricted group compared with the active group. Activated partial thromboplastin time, prothrombin time, and thromboplastin time were prolonged, but were shorter in the restricted group than in the active group. Serum IL-6, IL-8, and tumor necrosis factor-α levels were reduced in both groups and were lower in the restricted group than in the active group. The overall incidence of complications within 1 week of resuscitation was 7.50% (3/40) in the restricted group, which was lower than 25.00% (10/40) in the active group. The success rate of resuscitation within 1 week after resuscitation was 95.00% (38/40) higher in the restricted group than 77.50% (31/40) in the active group (all P < 0.05).
CONCLUSION: Compared with active fluid resuscitation, restrictive fluid resuscitation applied in the emergency treatment of THS patients has a better effect on the improvement of patients' blood gas indices, coagulation indices, and inflammation indices, and can effectively reduce the incidence of complications and enhance the success rate of resuscitation.