Immunization and Cardiovascular Disease in Latin America. The CorVacc Study: Results.
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Wyss Fernando, Lopez-Santi Ricardo, Piskorz Daniel, Gonzalez Horacio Márquez, Gutierrez Lucelli Yañez, Gupta Shyla, Munera-Echeverri Ana, Santi Pilar Lopez, Piskorz Gonzalo, Ullauri Vladimir, Gomez Juan Esteban, Del Sueldo Mildren, Almonte Claudia, Mendez Máxima, Valdez Osiris, Ponte-Negretti Carlos Ignacio, Rivera María Alayde Mendoça, Rivera Iván Romero, Barragan Adriana Puente, Villar Raúl, Effio Julio, Pineda Jorge Alberto Rivera, Berrospi Percy, Barrientos Ana Isabel, Silvera Nancy, Jordan Edmundo, Lopez Shirley Alejandrina Xiloj, Quezada Daniel, Arguello Ariel, Perez Gonzalo, Baranchuk Adrián, Corvacc Study Investigators
Аннотация
METHODS AND DESIGN: The Inter-American Registry of Influenza and Pneumococcal Vaccination (CorVacc Study) is a cross-sectional survey of the general population conducted across 19 Latin American countries. Adults aged 18 years and older completed a 34-question online survey. The pool was validated within the first 1000 responses. Data were grouped into seven categories: demographics, socioeconomic and educational level, cardiometabolic profile, cardiovascular interventions, medical follow-up and treatments, and COVID-19 vaccination status.
RESULTS: A total of 21,389 responses were obtained, distributed as follows: 8915 from the North, Central, and Caribbean region; 7492 from the Andean region; and 4801 from the Southern Cone region. Influenza vaccination rates were lower in the Andean region (OR: 0.62; 95% CI: 0.50-0.78), the Caribbean (OR: 0.30; 95% CI: 0.23-0.39), and Central America (OR: 0.59; 95% CI: 0.46-0.76) compared with the Southern Cone. Residing in Central America (OR: 3.06; 95% CI: 1.62-5.77) was associated with greater pneumococcal vaccination. The probability of being vaccinated against influenza was higher in men (OR: 1.3; 95% CI: 1.1-1.6) and in individuals with obesity (OR: 1.26; 95% CI: 1.13-1.40). COPD was associated with a lower probability of pneumococcal vaccination (OR: 0.51; 95% CI: 0.33-0.79).
CONCLUSIONS: This study highlights the importance of targeted vaccination campaigns to improve coverage, particularly in regions with lower rates. It also underscores the need for enhanced education and awareness of the benefits of vaccination. Tackling barriers such as vaccine hesitancy and misinformation will be essential for raising vaccination rates and, ultimately, for reducing the burden of cardiovascular disease.