GRAM-NEGATIVE BACTERIA FROM PATIENTS WITH ENDOPHTHALMITIS: DISTRIBUTION OF ISOLATES AND ANTIMICROBIAL SUSCEPTIBILITIES.

PURPOSE: To study the distribution of isolates and antimicrobial susceptibility of gram-negative bacteria among culture-positive vitreous samples from patients with endophthalmitis.

METHODS

The records from culture-positive vitreous isolates (endophthalmitis cases) during a 24-year period (December 1990 to December 2014), at the Microbiology Department of Bascom Palmer Eye Institute were reviewed.

RESULTS

In the current study, gram-negative bacteria were reported in 246 (11.5%) of 2,134 vitreous isolates from endophthalmitis patients during 24-year period (December 1990 to December 2014) from a University Referral Center. The antimicrobial susceptibility to fluoroquinolones, aminoglycosides, carbapenems, and ceftazidime remained stable among gram-negative bacteria during the study period.

CONCLUSION

Antibiotic susceptibility pattern of gram-negative bacteria from vitreous isolates did not change significantly during the 24-year study period.