Primary calvarial cryptococcal osteomyelitis in a patient with idiopathic lymphopenia.

An example of primary calvarial cryptococcal osteomyelitis in a patient with idiopathic lymphopenia is presented. The patient was a suboptimally immunocompetent host with an isolated skull involvement without any systemic infection. The Magnetic Resonance Imaging radiographic findings of the head are reviewed. The patient underwent surgical debridement of the lesion as well as receiving a course of oral antifungal medication. We discuss cryptococcal osteomyelitis and review the reports of cryptococcal disease and Idiopathic Lymphopenia.