BioMed research international · 2023
PHINDaccess Hackathons for COVID-19 and Host-Pathogen Interaction: Lessons Learned and Recommendations for Low- and Middle-Income Countries.
СтатьяНазвание и аннотация: Перевод в очереди
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Ghedira Kais, Dallali Hamza, Ardhaoui Monia, Bouslema Zied, Hamdi Yosr, Feki Ben-Salah Salma, Chelbi Hanen, Atri Chiraz, Chaouch Melek, Dekhil Naira, Rais Afef, Azouz Saifeddine, Gharbi Manel, Guerfali Fatma, Hkimi Chaima, Kamoun Selim, Ksouri Ayoub, Moumni Imen, Ouragini Houyem, Bsibes Raghda, Afifi Zeineb, Youssfi Khouloud, Ben Hassine Hichem, Hadhri Najet, Mardassi Helmi, Othman Houcemeddine, Khamessi Oussema
Аннотация
Hackathons are collaborative events that bring together diverse groups to solve predefined challenges. The COVID-19 pandemic caused by SARS-CoV-2 has emphasized the need for portable and reproducible genomics analysis pipelines to study the genetic susceptibility of the human host and investigate human-SARS-CoV-2 protein interactions. To build and strengthen institutional capacities in OMICS data analysis applied to host-pathogen interaction (HPI), the PHINDaccess project organized two hackathons in 2020 and 2021. These hackathons are aimed at developing bioinformatics pipelines related to the SARS-CoV-2 viral genome, its phylodynamic transmission, and the identification of human genome host variants, with a focus on addressing global health challenges, particularly in low- and middle-income countries (LMIC). This paper outlines the preparation, proceedings, and lessons learned from these hackathons, including the challenges faced by participants and our recommendations based on our experience for organizing hackathons in LMIC and beyond.