Медицинская библиотека · Oral surgery, oral medicine, oral pathology and oral radiology · 2012

Comparison of lidocaine metabolism for different anesthesia techniques in rabbits with liver disease.

Çelebi Nükhet, Muğlalı Mehtap, Aksoy Abdurrahman, Yarım Gül, Yarım Murat, Güvenç Dilek

Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

OBJECTIVE

This study was designed to investigate the serum lidocaine concentrations (SLC) after local infiltration anesthesia (IA) and mandibular anesthesias (MA) in rabbits with carbon tetrachloride (CCl₄)-induced chronic liver damage (CLD).

STUDY

DESIGN

Fourteen rabbits were administered CCl₄ in group 1, MA (CLD-MA; n = 7); in group 2, IA (CLD-IA; n = 7); in group 3, MA (H-MA; n = 7); and in group 4, IA (H-IA; n = 6) was performed. SLC were measured.

RESULTS

SLC showed difference over time. At the 10th minute, mean SLC in IA groups were higher than in MA groups. At the 120th minute, the highest mean concentration was found in the CLD-IA group.

CONCLUSIONS

SLC increases in CLD, and serum lidocaine concentration after IA in the mandibular anterior region is higher than it is after MA.

Для цитирования: Çelebi Nükhet, Muğlalı Mehtap, Aksoy Abdurrahman, Yarım Gül, Yarım Murat, Güvenç Dilek. Comparison of lidocaine metabolism for different anesthesia techniques in rabbits with liver disease.. Oral surgery, oral medicine, oral pathology and oral radiology. 2012. DOI: 10.1016/j.oooo.2011.11.026.

Предметные рубрики MeSH

Analysis of Variance Anesthesia, Local Anesthetics, Local Animals End Stage Liver Disease Lidocaine Male Mandible Rabbits

Подготовка и перевод публикации

Обработка статьи · этапы, ошибки и управление

Загрузка состояния…

История · было → стало

Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.