False-Positive 68Ga-DOTATATE PET/CT Findings in Hereditary Hypophosphatemia-Osteomalacia Mimicking Culprit Lesions of Tumor-Induced Osteomalacia.

68Ga-DOTATATE PET/CT is an important imaging modality for detection of culprit lesions of tumor-induced osteomalacia in clinically symptomatic patients with hypophosphatemia-osteomalacia. Somatostatin receptor expression may at times be observed in inflammatory or granulomatous conditions and in fractures or degenerative bone disease, leading to false-positive scan findings. We present a rare case of hereditary hypophosphatemia-osteomalacia that showed increased false-positive uptake (for possible tumor-induced osteomalacia lesions) in an inflammatory condition of the maxillary sinus and a fracture of the tibia on somatostatin receptor-based 68Ga-DOTATATE PET/CT.