Correlation Between End-Tidal Carbon Dioxide and Regional Cerebral Oxygen Saturation During Cardiopulmonary Resuscitation.

Background/

Objectives

Near-infrared spectroscopy (NIRS) enables the non-invasive assessment of cerebral oximetry, offering insights into the efficacy of oxygen supply to the brain. NIRS, when combined with other monitoring techniques such as capnography, may play a crucial role in advanced patient monitoring during sudden cardiac arrest and post-resuscitation treatment. This research assessed the relationship between end-tidal carbon dioxide (ETCO2) and regional cerebral oxygen saturation (rSO2) during cardiopulmonary resuscitation.

Methods

The research was performed from 11 January 2023 until 31 January 2024, at the University Hospital in Poland. The cohort of responders included patients who had in-hospital cardiac arrest (IHCA). The Rapid Response Team attached the rSO2 and ETCO2 monitoring devices to each patient during cardiopulmonary resuscitation (CPR). The cohort included 104 patients.

Results

The correlation coefficient between ETCO2 and rSO2 values was 0.641 (95% CI: 0.636-0.646), and during the last 4 min of CPR before ROSC, it was 0.873 (95% CI: 0.824-0.910).

Conclusions

The positive correlation between ETCO2 and rSO2 may suggest that concurrent monitoring of both parameters during resuscitation might serve as a valuable predictor of CPR efficacy and the likelihood of achieving recovery of spontaneous circulation in a multimodal framework. In the lack of rapid ETCO2 monitoring capabilities, rSO2 may function as a simple and effective alternative for assessment.