Transurethral Plasmakinetic Resection of the Prostate on Benign Prostatic Hyperplasia: Observation of Stress Injury and Analysis of Factors Associated with Postoperative Urinary Tract Infection.

OBJECTIVE

This study aimed to analyse stress injury in the treatment of benign prostatic hyperplasia (BPH) by transurethral plasmakinetic resection of the prostate (TUPKP), as well as the related factors affecting patients' urinary tract infection (UTI) after TUPKP for clinical reference.

METHODS

Retrospective analysis was conducted on patients with BPH who were admitted to our hospital from May 2022 to June 2024. Amongst them, the patients treated with TUPKP were the observation group, and the patients treated with electroprostatectomy (EP) were the control group. The surgical parameters, as well as the differences in inflammation, stress responses and urodynamics before and after surgery, were compared between the two cohorts. Subsequently, logistic regression analysis was performed to analyse the relevant factors affecting UTI after TUPKP.

RESULTS

A total of 219 patients were treated with TUPKP (observation group), and another 184 patients were treated with conventional EP (control group). The observation group showed shorter duration of indwelling urethral catheters and postoperative hospital stays as well as less intraoperative blood loss than the control group (p < 0.05). In addition, the inflammation and stress response in the observation group were milder 3 days after surgery, and the urodynamics were more favourable 3 months after surgery (p < 0.05). The incidence of UTI was 20.55% (45/219) in the observation group and 29.35% (54/184) in the control group. Logistic regression analysis demonstrated that diabetes mellitus (odds ratio (OR): 6.362, 95% CI: 2.232-8.132), urethral injury (OR: 5.476, 95% CI: 1.932-5.515), duration of indwelling urethral catheters (OR: 2.164, 95% CI: 1.204-3.889) and bladder irrigation times (OR: 0.051, 95% CI: 0.229-0.809) were independent determinants affecting UTI (p < 0.05).

CONCLUSIONS

TUPKP for the treatment of BPH can effectively attenuate postoperative inflammation and stress responses in patients. On the contrary, diabetes, urethral injury, duration of indwelling urethral catheter and bladder perfusion were the factors influencing the development of UTI after TUPKP.