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DOI 10.4103/0378-6323.187084

Медицинская библиотека · Indian journal of dermatology, venereology and leprology · 2016

Keloidectomy with core fillet flap and intralesional verapamil injection for recurrent earlobe keloids.

El-Kamel Mohammed Fawzy, Selim Mohamed K, Alghobary Moheiddin F

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Аннотация

BACKGROUND

Earlobe keloids are usually recalcitrant to treatment and have a high rate of recurrence. Verapamil is a calcium channel antagonist that has been shown to inhibit the synthesis/secretion of extracellular matrix molecules and increase collagenase.

OBJECTIVES

This prospective study was designed to evaluate the results of treatment of recurrent earlobe keloids using keloidectomy with core fillet flap and intralesional verapamil injection.

METHODS

Nineteen keloids in 16 patients were treated using this technique with intralesional verapamil injection given intraoperatively, then every 2 weeks for 3 months, with postoperative follow-up for 18 months.

RESULTS

Fourteen patients completed the study. Ten patients (71.4%) showed response to treatment. Four (28.6%) cases showed recurrence, two (14.2%) at the wound bed and another two (14. 2%) at the incision line. Eighty percent of responders were highly satisfied with their treatment.

CONCLUSION

Keloidectomy with core fillet flap and intralesional verapamil injection is a reliable and cost-effective method in the treatment of recurrent earlobe keloids with a low rate of recurrence and high patient satisfaction.

Для цитирования: El-Kamel Mohammed Fawzy, Selim Mohamed K, Alghobary Moheiddin F. Keloidectomy with core fillet flap and intralesional verapamil injection for recurrent earlobe keloids.. Indian journal of dermatology, venereology and leprology. 2016. DOI: 10.4103/0378-6323.187084.

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