[Disorders of psychoneurohumoral interrelations in patients suffering from arterial hypertension].

To elucidate disorders of psychoneurohumoral relationships in patients with grade I-II arterial hypertension at low, moderate and high overall cardiovascular risk, we measured body mass index, activity of sympathetic nervous system, serum leptin level and performed psychological tests aimed to elucidate situational and personal anxiety, aggressiveness and hostility. The data obtained allow a patient to be referred to one of the three possible types of disturbed psychoneurohumoral interrelations, viz. anxiety-metabolic, anxiety-adrenergic, and aggressive-metabolic, each having its own specific gender-related and clinical features. Discrimination between these types permits to substantiate pathogenetic therapy of arterial hypertension on an individual basis.