Periodic and non-periodic sleep apnea in premature and fullterm infants.

The sleep states of nine premature infants were observed and concomitant respiration recordings were obtained at 37 and 41 weeks conceptional age. 19 fullterm infants were also studied at 41 weeks conceptional age. Between 37 and 41 weeks significant decreases occurred in the premature infants' percentage of periodic apnea, rate of apnea in active sleep-REM, and length of the longest apneic episode. The premature and fullterm infants at 41 weeks did not differ in the frequency of apneic episodes, but the premature group had shorter episodes. These results provide additional evidence for the difference between premature and fullterm infants in central nervous system organization.