Eosinophilic Pleural Effusion Induced by Paliperidone Palmitate: Case Report and Literature Review.

BACKGROUND

Eosinophilic pleural effusions are defined by an eosinophil count ≥ 10% in pleural fluid and represent approximately 10% of exudative pleural effusions. They are associated with a large spectrum of etiologies, both benign and malignant. Drug-induced eosinophilic pleural effusions remain rarely described.

OBJECTIVE AND

METHODS

After ruling out other causes with a careful diagnostic assessment, we retain paliperidone as the etiology, given the disappearance of the pleural effusion after drug discontinuation.

RESULTS

We report the first case of eosinophilic pleural effusion induced by paliperidone palmitate treatment.

CONCLUSION

After considering other etiologies, drug-induced eosinophilic pleural effusion should be sought.