Epidemiological aspects of a St. Louis encephalitis outbreak in Harris County, Texas, 1986.

An outbreak of St. Louis encephalitis (SLE) resulted in 28 cases of the disease in Harris County, Texas, in 1986. The cases occurred principally in Baytown, in eastern Harris County, but five cases were also recognized in Houston. The risk of illness increased sharply with age, and all five fatal cases were in persons greater than 55 y. Case-control methods were used for the first time to study factors associated with the risk of acquiring SLE. Risk was associated with residences poorly sealed against mosquitoes (non-air-conditioned residences and those with inadequate screens). The number of hours spent outdoors and in outdoor activities, except sitting immediately outside residences, were not associated with risk. Our observations suggest that exposure to vector mosquitoes may have occurred indoors. No host factors were significantly associated with risk of acquiring SLE, but more cases were cigarette smokers and had family histories of hypertension or cerebrovascular disease.