Case reports in infectious diseases · 2026
Extraneurological Presentations of Tick-Borne Encephalitis Virus: A Rare Case of TBEV-Associated Myocarditis With Fever and Bicytopenia and a Systematic Literature Review.
СтатьяНазвание и аннотация: Перевод в очереди
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Seneghini Marco, Lugano Fabiola, Maeder Micha T, Garcia-Boy Regine, Strahm Carol
Аннотация
PURPOSE: Tick-borne encephalitis (TBE), a zoonotic disease caused by the tick-borne encephalitis virus (TBEV), usually manifests with a biphasic course with neurological involvement during its second phase. Extraneurological manifestations are rare but clinically relevant.
METHODS: We report a case of a 77-year-old patient with suspected acute myocarditis associated with central European TBEV infection and summarize the literature on extraneurological TBEV manifestations through a systematic review.
RESULTS: The case of a 77-year-old patient with suspected acute myocarditis associated with central European TBEV infection is reported and discussed. Literature analysis identified 23 publications reporting extraneurological TBEV manifestations, including (peri)myocarditis, myositis, hematological abnormalities, and elevated transaminases.
CONCLUSION: TBEV infection can be complicated by myocarditis and should therefore be considered in the differential diagnosis in areas where TBEV is endemic in a patient with risk factors for tick bites. Vaccination remains crucial for preventing TBEV infections.
METHODS: We report a case of a 77-year-old patient with suspected acute myocarditis associated with central European TBEV infection and summarize the literature on extraneurological TBEV manifestations through a systematic review.
RESULTS: The case of a 77-year-old patient with suspected acute myocarditis associated with central European TBEV infection is reported and discussed. Literature analysis identified 23 publications reporting extraneurological TBEV manifestations, including (peri)myocarditis, myositis, hematological abnormalities, and elevated transaminases.
CONCLUSION: TBEV infection can be complicated by myocarditis and should therefore be considered in the differential diagnosis in areas where TBEV is endemic in a patient with risk factors for tick bites. Vaccination remains crucial for preventing TBEV infections.