Prophylactic antibiotics in maxillofacial fractures: a requisite?

The role of prophylactic antibiotics to prevent surgical wound infection (SWI) in the management of maxillofacial fractures is controversial. We carried out a retrospective study in 67 patients with 114 maxillofacial fractures, of which 9 patients each were in group 1 (no antibiotic) and group 3 (cefotaxime) and 49 in group 2 (penicillin). We had an overall SWI rate of 16.66%, of which 3 of group 1 (33.33%), 12 of group 2 (24.48%), and 2 of group 3 (22.22%) constituted the SWIs. Statistical analysis showed no significant difference between the infection rates. A strong positive correlation was found between infection rate and the delay in treatment, and a similar correlation was found in the use of catgut and SWI. Our study suggests that prophylactic antibiotic therapy may not alter the incidence of surgical wound infection.