Orvosi hetilap · 2014
[Pathophysiological changes of umbilical vessels in intrauterine growth restriction].
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод в очереди
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Jakó Mária, Surányi Andrea, Kaiser László, Domokos Dóra, Gáspár Róbert, Bártfai György
Аннотация
INTRODUCTION: The prevalence of intrauterine growth restriction is 4-5000/100,000 births, and they give the majority of perinatal morbidity.
AIM: The aim of the authors was to compare the pathomorphologic data and vasoreactivity of umbilical vessels and placenta of small for date newborns to that of the normal pregnancies.
METHOD: Samples of the umbilical cord and placenta were divided into case and control groups. Two 10 cm long segments were cut of the umbilical cord at placental insertion. Tissue bath experiment was performed on umbilical vessels and pathomorphologic data were collected according to the Royal College of Pathologists' protocol.
RESULTS: After the development of basal tone, oxytocin and desmopressin did not enhance the vascular contraction, but the pathomorphological and ultrasonographic data were significantly different in the two groups.
CONCLUSIONS: The results indicate that umbilical vessels might not have oxytocin or vasopressin receptors. The pathomorphologic and flowmetric differences could be the causes of small birth weight.
AIM: The aim of the authors was to compare the pathomorphologic data and vasoreactivity of umbilical vessels and placenta of small for date newborns to that of the normal pregnancies.
METHOD: Samples of the umbilical cord and placenta were divided into case and control groups. Two 10 cm long segments were cut of the umbilical cord at placental insertion. Tissue bath experiment was performed on umbilical vessels and pathomorphologic data were collected according to the Royal College of Pathologists' protocol.
RESULTS: After the development of basal tone, oxytocin and desmopressin did not enhance the vascular contraction, but the pathomorphological and ultrasonographic data were significantly different in the two groups.
CONCLUSIONS: The results indicate that umbilical vessels might not have oxytocin or vasopressin receptors. The pathomorphologic and flowmetric differences could be the causes of small birth weight.