Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke · 1996
[Drug-induced photosensitivity in Norway. An analysis of reports from the period 1970-93].
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Аннотация
We have reviewed the data on unwanted side effects of drug therapy, as reported to the Norwegian Medicines Control Authority during the period 1970 to 1993. In all, 13,000 unwanted side effects were reported during this period. The number of recorded side effects was analysed especially in respect of unwanted reactions of the skin and appendages, and photosensitive reactions. 799 reported side effects involved the skin and appendages. Out of these, 64 reports (8%) were classified as being photosensitive reactions. Tetracyclines, diuretics and antihypertensive agents were the drugs most often causing photosensitive reactions, although several uncommon photosensitizing drugs were also reported. The actual risk of photosensitisation is discussed in the light of the prescriptions of these substances actually issued.