Veterinary anaesthesia and analgesia · 2021
Effect of preoxygenation before isoflurane induction and rocuronium-induced apnea on time until hemoglobin desaturation in domestic chickens (Gallus gallus domesticus).
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Legg-St Pierre Crystalyn, Desprez Isabelle, Chang Stephanie, Machin Karen, Ambros Barbara
Аннотация
OBJECTIVE: To evaluate the time to hemoglobin oxygen desaturation in chickens (Gallus gallus domesticus) with and without preoxygenation before isoflurane induction of anesthesia and rocuronium-induced apnea.
STUDY DESIGN: Prospective, randomized crossover study.
ANIMALS: A total of 10 healthy adult Lohmann Brown-Lite hens.
METHODS: Hens were anesthetized with isoflurane for intravenous (IV) and intraarterial catheter placement and allowed to fully recover from anesthesia. Hens in the preoxygenation treatment were administered oxygen (2 L minute-1) via a facemask for 3 minutes prior to induction of anesthesia with 3% isoflurane in oxygen. In the alternative treatment, hens were not preoxygenated prior to induction of anesthesia with isoflurane in oxygen. Apnea was then induced with rocuronium bromide (1.0 mg kg-1) administered IV, and anesthesia was maintained with IV propofol infusion. A cloacal pulse oximeter measured hemoglobin oxygen saturation (SpO2). Time was recorded from the start of apnea until SpO2 was 90% (desaturation). The trachea was intubated, and anesthesia was maintained with isoflurane in oxygen with manual ventilation until spontaneous breathing returned and SpO2 ≥ 99%. PaO2 was measured before each treatment, after preoxygenation, postinduction and at desaturation. Data were analyzed between treatments using Wilcoxon matched-pairs signed rank tests with Holm-Šidák multiple comparison test, and within treatments using Friedman test with Dunn's multiple comparison test (p < 0.05). Data are reported as median (range).
RESULTS: Time from start of apnea until hemoglobin desaturation was not significantly different between preoxygenated and nonpreoxygenated hens [26.5 (16-50) seconds and 24.0 (5-57) seconds, respectively; p = 0.25]. No differences in PaO2 between treatments were observed at any time point.
CONCLUSIONS AND CLINICAL RELEVANCE: Preoxygenation for 3 minutes before isoflurane mask induction of anesthesia and apnea does not significantly increase time until desaturation in hens.
STUDY DESIGN: Prospective, randomized crossover study.
ANIMALS: A total of 10 healthy adult Lohmann Brown-Lite hens.
METHODS: Hens were anesthetized with isoflurane for intravenous (IV) and intraarterial catheter placement and allowed to fully recover from anesthesia. Hens in the preoxygenation treatment were administered oxygen (2 L minute-1) via a facemask for 3 minutes prior to induction of anesthesia with 3% isoflurane in oxygen. In the alternative treatment, hens were not preoxygenated prior to induction of anesthesia with isoflurane in oxygen. Apnea was then induced with rocuronium bromide (1.0 mg kg-1) administered IV, and anesthesia was maintained with IV propofol infusion. A cloacal pulse oximeter measured hemoglobin oxygen saturation (SpO2). Time was recorded from the start of apnea until SpO2 was 90% (desaturation). The trachea was intubated, and anesthesia was maintained with isoflurane in oxygen with manual ventilation until spontaneous breathing returned and SpO2 ≥ 99%. PaO2 was measured before each treatment, after preoxygenation, postinduction and at desaturation. Data were analyzed between treatments using Wilcoxon matched-pairs signed rank tests with Holm-Šidák multiple comparison test, and within treatments using Friedman test with Dunn's multiple comparison test (p < 0.05). Data are reported as median (range).
RESULTS: Time from start of apnea until hemoglobin desaturation was not significantly different between preoxygenated and nonpreoxygenated hens [26.5 (16-50) seconds and 24.0 (5-57) seconds, respectively; p = 0.25]. No differences in PaO2 between treatments were observed at any time point.
CONCLUSIONS AND CLINICAL RELEVANCE: Preoxygenation for 3 minutes before isoflurane mask induction of anesthesia and apnea does not significantly increase time until desaturation in hens.