[Possible role of threonine metabolism in tetracycline biosynthesis].

The review presents the data on the metabolism of threonine and branched amino acids in actinomycetes. The data substantiate the hypothesis on the catabolism of carbohydrates through oxaloacetate--aspartate--threonine--ketomethyl valerate as an alternative pathway in the formation of acetyl-coA in the cells of tetracycline-producing cultures.